Active Ingredients

In our Sacred Hair Restore Serum

Ingredient List

Aqua, Glycerin, Cucurbita Pepo Seed Oil, Nigella Sativa Seed Oil, Alcohol, Serenoa Serrulata Fruit Extract, Mentha Piperita Oil, Rosmarinus Officinalis Leaf Oil, Camellia Sinensis Leaf Extract, Panax Ginseng Root Extract, Centella Asiatica Extract, Niacinamide, Polysorbate 20, Caffeine, Magnesium Chloride, Tocopherol, Bromelain, Adenosine

Rosemary Essential Oil

Rosemary Essential Oil

Rosemary oil contains rosmarinic acid, carnosic acid, and ursolic acid —compounds proven to match 2% minoxidil's effectiveness without irritation in a 2015 study by Panahi et al. published in SKINmed Journal. This powerful botanical works through multiple pathways: enhancing scalp circulation by up to 37% to deliver vital nutrients to follicles (as demonstrated in Takaki et al.'s 2013 research on rosemary's vasodilatory effects), naturally blocking DHT—the primary cause of pattern hair loss—by inhibiting 5-alpha-reductase enzyme (confirmed in Murata et al.'s 2013 study on rosemary extract), and creating optimal scalp health through antimicrobial and anti-inflammatory properties (verified in Tsai et al.'s 2013 investigation of rosemary's antimicrobial activities) for maximum hair restoration results with zero irritation.

Peppermint Essential Oil

Peppermint Essential Oil

A 2014 study by Oh et al. published in Toxicological Research demonstrated peppermint oil's ability to promote hair growth, outperforming 3% minoxidil with a 92% increase in dermal thickness and 20% greater follicle depth. This powerful botanical stimulates rapid blood circulation to hair follicles (confirmed in Meier et al.'s 2015 research on peppermint's vasodilatory properties), significantly increases IGF-1 and alkaline phosphatase—key growth factors for hair development (as verified in Park et al.'s 2016 study), and creates an optimal scalp environment through potent antimicrobial and anti-inflammatory actions (demonstrated in Soković et al.'s comprehensive 2010 investigation of peppermint's biological properties).

Pumpkin Seed Oil

Pumpkin Seed Oil

Pumpkin Seed Oil is rich in beta-sitosterol, a plant sterol shown to inhibit 5-alpha-reductase—the enzyme that converts testosterone into DHT, a primary cause of pattern hair loss (Gossell-Williams et al., 2006). When applied to the scalp, it helps reduce follicle miniaturization and supports stronger, denser hair growth.

Packed with linoleic acid, zinc, and antioxidants like vitamin E and carotenoids, it nourishes the scalp, strengthens hair structure, and protects follicles from oxidative stress (Stevenson et al., 2007; Murkovic et al., 2004).

Although the 2014 clinical study by Cho et al. demonstrated oral supplementation led to a 40% increase in hair count, these findings support Pumpkin Seed Oil’s mechanism of action, which may also be effective when applied topically (Cho et al., 2014).

Black Seed Oil

Black Seed Oil

Primary active constituent, thymoquinone found in black seed oil, delivers potent anti-inflammatory and antioxidant actions, shielding follicles from oxidative stress and inflammation ResearchGateMDPI. Topical application supports scalp health by reducing microbial overgrowth and clearing blocked follicles, promoting an optimal growth environment PMCMDPI. Clinical studies have shown significant gains in hair density and thickness over three months, with subjects experiencing up to a 70% improvement in hair parameters GasheePMC. Rich in essential fatty acids and phytosterols, it strengthens hair shafts, decreases breakage, and revitalizes follicle vitality ResearchGatePMC.

Caffeine Extract

Caffeine Extract

Caffeine Extract harnesses its dual-action phosphodiesterase inhibition and 5-alpha-reductase suppression to stimulate hair growth directly at the follicle level (Brandner et al., 2007 PMC; Herman & Herman, 2013 XYON). When applied topically, it rapidly penetrates the scalp, enhancing microcirculation for improved nutrient delivery and oxygenation of hair roots (New Image Hair Clinic, 2022 newimagehairclinic.com; ShearPointe, 2024 shearpointe.com). In vitro, caffeine at just 0.001% concentration counteracts testosterone-induced hair inhibition, promoting significant shaft elongation over 120 hours (In Vitro Study, 2007 ResearchGate; PMC, 2013 PMC). A multicenter clinical trial confirmed that daily use of a 0.2% caffeine lotion reduced hair shedding by 15.3% at four months, with 83% of participants showing positive pull-test responses (PMC, 2018 PMC). Caffeine’s antioxidant capacity also protects follicles from oxidative damage, preserving strength and minimizing breakage (Healthline, 2019 Healthline; PMCID, 2024 PMC).

Saw Palmetto Extract

Saw Palmetto Extract

Saw Palmetto Extract tackles concentrated phytosterols to inhibit 5-alpha-reductase, blocking DHT at the follicle and reducing hair miniaturization (VISPO Study, 16-Week Trial PubMed; 2012 Androgenetic Alopecia Study hims). When applied topically, it boosts microcirculation to fuel hair growth and strength hims. Clinical data show a 22% reduction in hair fall and up to a 7.6% increase in density after 16 weeks of topical use, with notable gains in thickness and resilience (VISPO Study PubMed; Morningstar Report Морнингстар). Its antioxidant-rich profile also offers long-term protection against oxidative stress, supporting sustained follicle vitality.

Green Tea Extract

Green Tea Extract

Green Tea Extract delivers high concentrations of EGCG (epigallocatechin-3-gallate) that selectively inhibit 5α-reductase, reducing DHT and preventing follicle miniaturization PubMedWiley Online Library. EGCG also stimulates dermal papilla cell proliferation by activating ERK and Akt signaling pathways, key drivers of the hair growth cycle. Additionally, green tea tonics can regulate scalp sebum, promoting a balanced environment for growth ResearchGate.

Bromelain

Bromelain

Scalp Exfoliation: Breaks down dead skin cells and excess oil to unclog follicles and boost absorption of other actives Soteri Skin.

Anti-Inflammatory Care: Soothes irritation and redness, creating a calm environment where hair can thrive FullyVital.

Anti-Fibrotic Action: Helps prevent collagen over-buildup (fibrosis) around follicles, so nutrients reach hair roots more easily HairLossTalk.

Calcification Prevention: By reducing chronic inflammation, it may also slow mineral deposits that stiffen the scalp matrix Low Toxin Forum.

Enhanced Delivery: Its proteolytic activity gently increases scalp permeability, letting co-applied ingredients penetrate deeper FullyVital.

Magnesium Chloride

Magnesium Chloride

Magnesium chloride helps dissolve calcium deposits caused by hard water and mineral buildup, which can clog follicles and stunt hair growth ByrdieNina Ross Hair Therapy. By restoring calcium balance on the scalp, it prevents mineral-induced follicle obstruction and supports healthy hair cycling Clinikally.

It regulates enzymes involved in inflammation and tissue remodeling, thereby reducing fibrosis and preventing scalp stiffening Salt Lab. As a natural anti-inflammatory, topical magnesium soothes irritation, redness, and itching BehrhausSalt Lab.

Centella Asiatica Extract

Centella Asiatica Extract

Boosts Microcirculation: Rich in triterpenes (asiaticoside, madecassoside), Centella Asiatica promotes blood flow in the scalp, ensuring hair follicles receive vital oxygen and nutrients for growth Typology ParisFullyVital.

Stimulates Collagen & Fibroblasts: Asiaticoside and madecassoside have been shown to increase fibroblast proliferation and type I collagen synthesis, strengthening the follicle’s extracellular matrix and anchoring hair roots more securely PMCTaylor & Francis Online.

Enhances Growth Signals: In human dermal papilla cell models, Centella Asiatica extract upregulates VEGF expression and inhibits STAT signaling pathways, driving hair-inductive properties and supporting the anagen (growth) phase ResearchGateResearchGate.

Niacinamide

Niacinamide

Barrier Enhancement: Niacinamide strengthens the scalp’s lipid barrier by boosting ceramide synthesis, which helps lock in moisture and protect follicles from external stressors TrichoLab.

Anti-Inflammatory & Sebum Regulation: It down-regulates pro-inflammatory cytokines and normalizes oil production, reducing redness, itchiness, and folliculitis that can impede growth AbyssianTrichoLab.

Vitamin E

Vitamin E

Vitamin E supports the scalp and gives your hair a strong base to grow from by reducing oxidative stress and preserving the protective lipid layer. Vitamin E also helps repair damaged hair by /cell-nourishment, reducing hair breakage, and improving your hair's elasticity and shine

Adenosine

Adenosine

Adenosine activates adenosine receptors in dermal papilla cells, leading to the upregulation of growth factors such as Fibroblast Growth Factor-7 (FGF-7) and Vascular Endothelial Growth Factor (VEGF), which are crucial for hair growth .